Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM146675'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM146675 (US8957073, 4.9 | US9718803, 4.9) Show SMILES Cc1cc(cnc1F)-c1nccnc1C1CN(C1)c1ccc2ccccc2n1 Show InChI InChI=1S/C22H18FN5/c1-14-10-16(11-26-22(14)23)20-21(25-9-8-24-20)17-12-28(13-17)19-7-6-15-4-2-3-5-18(15)27-19/h2-11,17H,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0120	n/a	n/a	n/a	n/a	n/a	25
Amgen Inc. US Patent					Assay Description An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 L of serial diluted PDE10A (BPS Bioscien...				US Patent US9718803 (2017) BindingDB Entry DOI: 10.7270/Q2J968DN
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM146675 (US8957073, 4.9 | US9718803, 4.9) Show SMILES Cc1cc(cnc1F)-c1nccnc1C1CN(C1)c1ccc2ccccc2n1 Show InChI InChI=1S/C22H18FN5/c1-14-10-16(11-26-22(14)23)20-21(25-9-8-24-20)17-12-28(13-17)19-7-6-15-4-2-3-5-18(15)27-19/h2-11,17H,12-13H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0122	n/a	n/a	n/a	n/a	n/a	25
Amgen Inc. US Patent					Assay Description Enzyme Activity. An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 uL of serial diluted PD...				US Patent US8957073 (2015) BindingDB Entry DOI: 10.7270/Q2PR7TPZ
					More data for this Ligand-Target Pair