Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM156305'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156305 (US9018217, 2-(6-Chloro-imidazo[1,2-a]pyridin-2-ylm...) Show SMILES Nn1cc(nc1SCc1cn2cc(Cl)ccc2n1)-c1ccccc1 Show InChI InChI=1S/C17H14ClN5S/c18-13-6-7-16-20-14(9-22(16)8-13)11-24-17-21-15(10-23(17)19)12-4-2-1-3-5-12/h1-10H,11,19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9592230 (2017) BindingDB Entry DOI: 10.7270/Q2CV4KSH
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM156305 (US9018217, 2-(6-Chloro-imidazo[1,2-a]pyridin-2-ylm...) Show SMILES Nn1cc(nc1SCc1cn2cc(Cl)ccc2n1)-c1ccccc1 Show InChI InChI=1S/C17H14ClN5S/c18-13-6-7-16-20-14(9-22(16)8-13)11-24-17-21-15(10-23(17)19)12-4-2-1-3-5-12/h1-10H,11,19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	830	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9018217 (2015) BindingDB Entry DOI: 10.7270/Q2KW5DS1
					More data for this Ligand-Target Pair