Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM204627'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM204627 (1-(5-butoxy-2-chloro-phenyl)-4-methyl-[1,2,4]triaz...) Show SMILES CCCCOc1ccc(Cl)c(c1)-c1nnc2c(C)nc3ccccc3n12 Show InChI InChI=1S/C20H19ClN4O/c1-3-4-11-26-14-9-10-16(21)15(12-14)20-24-23-19-13(2)22-17-7-5-6-8-18(17)25(19)20/h5-10,12H,3-4,11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...				Citation and Details BindingDB Entry DOI: 10.7270/Q2CR5XK9
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM204627 (1-(5-butoxy-2-chloro-phenyl)-4-methyl-[1,2,4]triaz...) Show SMILES CCCCOc1ccc(Cl)c(c1)-c1nnc2c(C)nc3ccccc3n12 Show InChI InChI=1S/C20H19ClN4O/c1-3-4-11-26-14-9-10-16(21)15(12-14)20-24-23-19-13(2)22-17-7-5-6-8-18(17)25(19)20/h5-10,12H,3-4,11H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The DNA of PDE10A1 (AB 020593, 2340 bp) was synthesized and cloned into the vector pCR4. TOPO (Entelechon GmbH, Regensburg, Germany). The gene was th...				US Patent US9540379 (2017) BindingDB Entry DOI: 10.7270/Q2RB72SP
					More data for this Ligand-Target Pair