Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM239754'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM239754 (US9394311, 37) Show SMILES Cc1ccc(C)n2nc(CCc3nc(nn3C)N3CCCC3)nc12 Show InChI InChI=1S/C17H23N7/c1-12-6-7-13(2)24-16(12)18-14(20-24)8-9-15-19-17(21-22(15)3)23-10-4-5-11-23/h6-7H,4-5,8-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM239754 (US9394311, 37) Show SMILES Cc1ccc(C)n2nc(CCc3nc(nn3C)N3CCCC3)nc12 Show InChI InChI=1S/C17H23N7/c1-12-6-7-13(2)24-16(12)18-14(20-24)8-9-15-19-17(21-22(15)3)23-10-4-5-11-23/h6-7H,4-5,8-11H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.21	n/a	n/a	n/a	n/a	n/a	25
Hoffmann-La Roche Inc. US Patent					Assay Description The human PDE10A full length assay was performed in 96-well micro titer plates. The reaction mixture of 50 μl contained 20 mM HEPES pH=7.5/10 mM M...				US Patent US9394311 (2016) BindingDB Entry DOI: 10.7270/Q27D2T2H
					More data for this Ligand-Target Pair