Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50049935'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50049935 (CHEMBL3317692) Show SMILES Cc1cc2c3ccccc3cc(CCc3nc4ccccc4n3C)n2n1 Show InChI InChI=1S/C22H20N4/c1-15-13-21-18-8-4-3-7-16(18)14-17(26(21)24-15)11-12-22-23-19-9-5-6-10-20(19)25(22)2/h3-10,13-14H,11-12H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Sassari Curated by ChEMBL					Assay Description Inhibition of human PDE10A (amino acids 14 to 779) using [3H]-labelled cyclic nucleotide as substrate after 1 hr b beta counting				Eur J Med Chem 84: 181-93 (2014) Article DOI: 10.1016/j.ejmech.2014.07.020 BindingDB Entry DOI: 10.7270/Q2S1844K
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