Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50390159'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Mus musculus)	BDBM50390159 (CHEMBL2069696) Show SMILES COc1cc(\C=N\NC(=O)C(OC(C)C)c2ccc(cc2)N2CCOCC2)cc(OC)c1Br Show InChI InChI=1S/C24H30BrN3O5/c1-16(2)33-23(18-5-7-19(8-6-18)28-9-11-32-12-10-28)24(29)27-26-15-17-13-20(30-3)22(25)21(14-17)31-4/h5-8,13-16,23H,9-12H2,1-4H3,(H,27,29)/b26-15+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Omeros Corp. Curated by ChEMBL					Assay Description Inhibition of mouse PDE10A-mediated hydrolysis of [3H]cGMP to [3H]GMP after 20 mins by scintillation counting				Bioorg Med Chem Lett 22: 5595-9 (2012) Article DOI: 10.1016/j.bmcl.2012.07.007 BindingDB Entry DOI: 10.7270/Q2X63P65
					More data for this Ligand-Target Pair