Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM50493163'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50493163 (CHEMBL2419370) Show SMILES CN(C(=O)c1ccncc1)c1ccc(OCc2cn3ccccc3n2)cc1 Show InChI InChI=1S/C21H18N4O2/c1-24(21(26)16-9-11-22-12-10-16)18-5-7-19(8-6-18)27-15-17-14-25-13-3-2-4-20(25)23-17/h2-14H,15H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Inhibition of PDE10A (unknown origin)				Bioorg Med Chem 21: 6053-62 (2013) Article DOI: 10.1016/j.bmc.2013.07.030 BindingDB Entry DOI: 10.7270/Q27P929Z
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