Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM99011'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Rattus norvegicus (rat))	BDBM99011 (US8497265, 467) Show SMILES Cc1ccc(cn1)-c1cnc(nc1OC1CN(C1)c1ccc2ccccc2n1)N1CCC(CO)CC1 Show InChI InChI=1S/C28H30N6O2/c1-19-6-7-22(14-29-19)24-15-30-28(33-12-10-20(18-35)11-13-33)32-27(24)36-23-16-34(17-23)26-9-8-21-4-2-3-5-25(21)31-26/h2-9,14-15,20,23,35H,10-13,16-18H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
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