Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM99012'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Rattus norvegicus (rat))	BDBM99012 (US8497265, 468) Show SMILES OCC1CCN(CC1)c1ncc(C2=CCOCC2)c(OC2CN(C2)c2ccc3ccccc3n2)n1 |t:13| Show InChI InChI=1S/C27H31N5O3/c33-18-19-7-11-31(12-8-19)27-28-15-23(20-9-13-34-14-10-20)26(30-27)35-22-16-32(17-22)25-6-5-21-3-1-2-4-24(21)29-25/h1-6,9,15,19,22,33H,7-8,10-14,16-18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
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