Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A' and Ligand = 'BDBM99052'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Rattus norvegicus (rat))	BDBM99052 (US8497265, 736 | US8497265, 797) Show SMILES O=C(N1CC(C1)Oc1ncccc1C1=CCOCC1)c1nc2ccccc2[nH]1 |t:15| Show InChI InChI=1S/C21H20N4O3/c26-21(19-23-17-5-1-2-6-18(17)24-19)25-12-15(13-25)28-20-16(4-3-9-22-20)14-7-10-27-11-8-14/h1-7,9,15H,8,10-13H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.864	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Rattus norvegicus (rat))	BDBM99052 (US8497265, 736 | US8497265, 797) Show SMILES O=C(N1CC(C1)Oc1ncccc1C1=CCOCC1)c1nc2ccccc2[nH]1 |t:15| Show InChI InChI=1S/C21H20N4O3/c26-21(19-23-17-5-1-2-6-18(17)24-19)25-12-15(13-25)28-20-16(4-3-9-22-20)14-7-10-27-11-8-14/h1-7,9,15H,8,10-13H2,(H,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.864	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. US Patent					Assay Description Enzyme activity: An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale, Calif).				US Patent US8497265 (2013) BindingDB Entry DOI: 10.7270/Q2VD6X39
					More data for this Ligand-Target Pair