Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779]' and Ligand = 'BDBM197748'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779] (Homo sapiens (Human))	BDBM197748 (US9216986, 4-Chloro-8-fluoro-2-[(E)-2-(8-methoxy-5...) Show SMILES COc1ccc(C)n2nc(\C=C\c3cc(Cl)c4cccc(F)c4n3)nc12 Show InChI InChI=1S/C19H14ClFN4O/c1-11-6-8-16(26-2)19-23-17(24-25(11)19)9-7-12-10-14(20)13-4-3-5-15(21)18(13)22-12/h3-10H,1-2H3/b9-7+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9216986 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XG5
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