Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779]' and Ligand = 'BDBM197770'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A [440-779] (Homo sapiens (Human))	BDBM197770 (US9216986, 6-[2-(5,8-Dimethyl-[1,2,4]triazolo[1,5-...) Show SMILES Cc1cnc(C)c2nc(CCc3ccc4cc5OC(F)(F)Oc5cc4n3)nn12 Show InChI InChI=1S/C19H15F2N5O2/c1-10-9-22-11(2)18-24-17(25-26(10)18)6-5-13-4-3-12-7-15-16(8-14(12)23-13)28-19(20,21)27-15/h3-4,7-9H,5-6H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	25
H. Lundbeck A/S US Patent					Assay Description A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...				US Patent US9216986 (2015) BindingDB Entry DOI: 10.7270/Q2Z31XG5
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