BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'cAMP-dependent protein kinase catalytic subunit alpha' and Ligand = 'BDBM27248'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cAMP-dependent protein kinase catalytic subunit alpha (Mus musculus (mouse))	BDBM27248 (6-{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-di...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Chemistry in Estonia					Assay Description The IC50 values of the inhibitors corresponding to the concentration of the inhibitor decreasing the enzyme activity 50% were measured using fluoresc...				J Med Chem 52: 308-21 (2009) Article DOI: 10.1021/jm800797n BindingDB Entry DOI: 10.7270/Q2RX99FQ
Institute of Chemistry in Estonia					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human))	BDBM27248 (6-{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-di...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic and Bioorganic Chemistry Curated by ChEMBL					Assay Description Inhibitory potency towards human cAPK C alpha in the presence of 100uM ATP and 30uM TAMRA-kemptide				J Med Chem 49: 7150-9 (2006) Article DOI: 10.1021/jm0605942 BindingDB Entry DOI: 10.7270/Q2542N79
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Homo sapiens (Human))	BDBM27248 (6-{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-di...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.30	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Organic and Bioorganic Chemistry Curated by ChEMBL					Assay Description Inhibitory potency towards human cAPK C alpha in the presence of 100uM ATP and 30uM TAMRA-kemptide				J Med Chem 49: 7150-9 (2006) Article DOI: 10.1021/jm0605942 BindingDB Entry DOI: 10.7270/Q2542N79
					More data for this Ligand-Target Pair