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Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50017107'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))
BDBM50017107
PNG
(1-Benzyl-4-(3,4-dimethoxy-phenyl)-pyrrolidin-2-one...)
Show SMILES COc1ccc(cc1OC)C1CN(Cc2ccccc2)C(=O)C1
Show InChI InChI=1S/C19H21NO3/c1-22-17-9-8-15(10-18(17)23-2)16-11-19(21)20(13-16)12-14-6-4-3-5-7-14/h3-10,16H,11-13H2,1-2H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Centre de Neurochimie du CNRS

Curated by ChEMBL


Assay Description
Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.


J Med Chem 32: 1450-7 (1989)


BindingDB Entry DOI: 10.7270/Q2DN441H
More data for this
Ligand-Target Pair