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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50017120'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50017120
PNG
(CHEMBL284512 | N-Cyclohexyl-4-[2-methoxy-5-(5-oxo-...)
Show SMILES COc1ccc(cc1OCCCC(=O)N(C)C1CCCCC1)C1CNC(=O)C1
Show InChI InChI=1S/C22H32N2O4/c1-24(18-7-4-3-5-8-18)22(26)9-6-12-28-20-13-16(10-11-19(20)27-2)17-14-21(25)23-15-17/h10-11,13,17-18H,3-9,12,14-15H2,1-2H3,(H,23,25)
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PC cid
PC sid
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Similars
PubMed
n/an/a 3.40E+4n/an/an/an/an/an/a



Centre de Neurochimie du CNRS

Curated by ChEMBL


Assay Description
Inhibitory activity against phosphodiesterase was determined in vitro using bovine aorta, at 1 uM cAMP for cAMP-PDE.

J Med Chem 32: 1450-7 (1989)


BindingDB Entry DOI: 10.7270/Q2DN441H
More data for this
Ligand-Target Pair