Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50216299'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50216299 (CHEMBL315529) Show SMILES COc1ccc(cc1OC1CCCC1)C(CC#N)N1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C23H22N2O4/c1-28-20-11-10-15(14-21(20)29-16-6-2-3-7-16)19(12-13-24)25-22(26)17-8-4-5-9-18(17)23(25)27/h4-5,8-11,14,16,19H,2-3,6-7,12H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of PDE4 enzyme from U937 cells				Bioorg Med Chem Lett 8: 2669-74 (1998) BindingDB Entry DOI: 10.7270/Q2BK1FJH
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