Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50470781'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50470781 (CHEMBL281781) Show SMILES COc1ccc(cc1OC1Cc2ccccc2C1)-c1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H20O4/c1-26-21-11-10-19(15-6-8-16(9-7-15)23(24)25)14-22(21)27-20-12-17-4-2-3-5-18(17)13-20/h2-11,14,20H,12-13H2,1H3,(H,24,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Phosphodiesterase 4				J Med Chem 39: 120-5 (1996) Article DOI: 10.1021/jm9505066 BindingDB Entry DOI: 10.7270/Q20P12Q4
					More data for this Ligand-Target Pair