Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50471931'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50471931 (CHEMBL341615) Show SMILES Clc1nc2c(nc(nc2nc1N1CCCC1)N1CCNCC1)N1CCCC1 Show InChI InChI=1S/C18H25ClN8/c19-14-17(26-9-3-4-10-26)22-15-13(21-14)16(25-7-1-2-8-25)24-18(23-15)27-11-5-20-6-12-27/h20H,1-12H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
University of Kaiserslautern Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by inhibiting phosphodiesterases (PDE4), isolated from tumor tissue of human large cell lung tumor xenograft LXFL-529, ...				J Med Chem 41: 4733-43 (1998) Article DOI: 10.1021/jm981021v BindingDB Entry DOI: 10.7270/Q2SN0CQ8
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