Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50472187'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50472187 (CHEMBL169746) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCC(=O)C1 Show InChI InChI=1S/C17H22O3/c1-19-16-9-7-13(12-6-8-14(18)10-12)11-17(16)20-15-4-2-3-5-15/h7,9,11-12,15H,2-6,8,10H2,1H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition activity against human monocyte derived PDE4 catalytic activity (LPDE4)				J Med Chem 41: 821-35 (1998) Article DOI: 10.1021/jm970090r BindingDB Entry DOI: 10.7270/Q2WD439M
					More data for this Ligand-Target Pair