Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D' and Ligand = 'BDBM50473079'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D (Homo sapiens (Human))	BDBM50473079 (CHEMBL145258) Show SMILES Nc1cc2CCN3c2c(c1)C(=N[C@@H](NC(=O)c1cc2ccccc2cn1)C3=O)c1ccccc1 |c:12| Show InChI InChI=1S/C27H21N5O2/c28-20-12-18-10-11-32-24(18)21(14-20)23(16-6-2-1-3-7-16)30-25(27(32)34)31-26(33)22-13-17-8-4-5-9-19(17)15-29-22/h1-9,12-15,25H,10-11,28H2,(H,31,33)/t25-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase type 4 isozyme (PDE4) from the U937 human cell line.				J Med Chem 43: 4850-67 (2000) Article DOI: 10.1021/jm000315p BindingDB Entry DOI: 10.7270/Q25M68FS
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