Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM332094'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM332094 (US10189854, Compound 48 | [1-[5-(3-Methoxyphenyl)-...) Show SMILES COc1cccc(c1)-c1cnc(nc1)N1CC2(CC2)c2ccc(cc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C26H26N4O3/c1-32-21-4-2-3-18(13-21)20-15-27-25(28-16-20)30-17-26(7-8-26)22-6-5-19(14-23(22)30)24(31)29-9-11-33-12-10-29/h2-6,13-16H,7-12,17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GRUENENTHAL GMBH US Patent					Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...				US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4
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