Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM332111'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM332111 (3-Fluoro-N,N-dimethyl-4-[2-[6-(morpholine-4-carbon...) Show SMILES CN(C)C(=O)c1ccc(c(F)c1)-c1cnc(nc1)N1CC2(CC2)c2ccc(cc12)C(=O)N1CCOCC1 Show InChI InChI=1S/C28H28FN5O3/c1-32(2)25(35)18-3-5-21(23(29)13-18)20-15-30-27(31-16-20)34-17-28(7-8-28)22-6-4-19(14-24(22)34)26(36)33-9-11-37-12-10-33/h3-6,13-16H,7-12,17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GRUENENTHAL GMBH US Patent					Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...				US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4
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