Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM332147'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM332147 (US10189854, Compound 103 | [1-[5-(2-Fluorophenyl)-...) Show SMILES CC1COCCN1C(=O)c1ccc2c(c1)N(CC21CC1)c1ncc(cn1)-c1ccccc1F Show InChI InChI=1S/C26H25FN4O2/c1-17-15-33-11-10-30(17)24(32)18-6-7-21-23(12-18)31(16-26(21)8-9-26)25-28-13-19(14-29-25)20-4-2-3-5-22(20)27/h2-7,12-14,17H,8-11,15-16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
GRUENENTHAL GMBH US Patent					Assay Description The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...				US Patent US10189854 (2019) BindingDB Entry DOI: 10.7270/Q2N87CW4
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