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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50256184'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50256184
PNG
(CHEMBL4074212)
Show SMILES COc1cccc(Nc2cc(nc3CCNC(=O)c23)-c2cccc(c2)-c2cc(ccc2O)C(O)=O)c1
Show InChI InChI=1S/C28H23N3O5/c1-36-20-7-3-6-19(14-20)30-24-15-23(31-22-10-11-29-27(33)26(22)24)17-5-2-4-16(12-17)21-13-18(28(34)35)8-9-25(21)32/h2-9,12-15,32H,10-11H2,1H3,(H,29,33)(H,30,31)(H,34,35)
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 9.60n/an/an/an/an/an/a



Medicinal Chemistry& Screening ,?Pharmacokinetics& Metabolism , and§Experimental Dermatology , Almirall S.A., Centro de Investigación y Desarrollo , Crta. Laureà Miró 408-410 , Sant Feliu de

Curated by ChEMBL


Assay Description
Inhibition of platelet derived growth factor receptor beta phosphorylation in MG63 cells in the presence of human plasma

J Med Chem 61: 2472-2489 (2018)


Article DOI: 10.1021/acs.jmedchem.7b01751
BindingDB Entry DOI: 10.7270/Q2HQ42BB
More data for this
Ligand-Target Pair