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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50457942'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B


(Homo sapiens (Human))		BDBM50457942
PNG
(CHEMBL4217546)
Show SMILES Cn1c2nc(NCc3ccccc3)n(CCCC(=O)N\N=C\c3ccc(O)cc3O)c2c(=O)n(C)c1=O
Show InChI InChI=1S/C25H27N7O5/c1-30-22-21(23(36)31(2)25(30)37)32(24(28-22)26-14-16-7-4-3-5-8-16)12-6-9-20(35)29-27-15-17-10-11-18(33)13-19(17)34/h3-5,7-8,10-11,13,15,33-34H,6,9,12,14H2,1-2H3,(H,26,28)(H,29,35)/b27-15+
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.50E+3n/an/an/an/an/an/a



Jagiellonian University

Curated by ChEMBL


Assay Description
Inhibition of human GST-tagged PDE4B expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...

Eur J Med Chem 146: 381-394 (2018)


Article DOI: 10.1016/j.ejmech.2018.01.068
BindingDB Entry DOI: 10.7270/Q2XD1496
More data for this
Ligand-Target Pair