Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50470729'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470729 (CHEMBL284970) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(S)=N Show InChI InChI=1S/C17H24N2O2S/c1-20-15-7-6-12(13-8-9-19(11-13)17(18)22)10-16(15)21-14-4-2-3-5-14/h6-7,10,13-14H,2-5,8-9,11H2,1H3,(H2,18,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
					More data for this Ligand-Target Pair