Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50491690'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50491690 (CHEMBL2387441) Show SMILES COc1ccc(cc1-c1cnc(OC)nc1OC)C1=Nc2c(nn(CCCO)c2C(=O)NC1)C(C)(C)C |t:20| Show InChI InChI=1S/C26H32N6O5/c1-26(2,3)22-20-21(32(31-22)10-7-11-33)23(34)27-14-18(29-20)15-8-9-19(35-4)16(12-15)17-13-28-25(37-6)30-24(17)36-5/h8-9,12-13,33H,7,10-11,14H2,1-6H3,(H,27,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE4B catalytic domain (unknown origin)				Bioorg Med Chem Lett 23: 3443-7 (2013) Article DOI: 10.1016/j.bmcl.2013.03.082 BindingDB Entry DOI: 10.7270/Q2C53PR1
					More data for this Ligand-Target Pair