Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50495763'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50495763 (CHEMBL3114944) Show SMILES OC(=O)Cc1ccc(Nc2nc(nc3CCCS(=O)(=O)c23)-c2ccc3c(F)cccc3c2)cc1 Show InChI InChI=1S/C25H20FN3O4S/c26-20-4-1-3-16-14-17(8-11-19(16)20)24-28-21-5-2-12-34(32,33)23(21)25(29-24)27-18-9-6-15(7-10-18)13-22(30)31/h1,3-4,6-11,14H,2,5,12-13H2,(H,30,31)(H,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 mins				Bioorg Med Chem Lett 24: 893-9 (2014) Article DOI: 10.1016/j.bmcl.2013.12.076 BindingDB Entry DOI: 10.7270/Q2GX4FHW
					More data for this Ligand-Target Pair