Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4B' and Ligand = 'BDBM50495780'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50495780 (CHEMBL3114951) Show SMILES COc1ccc(cc1F)-c1nc2CCCS(=O)(=O)c2c(Nc2ccc(CC(O)=O)c(Cl)c2)n1 Show InChI InChI=1S/C22H19ClFN3O5S/c1-32-18-7-5-13(9-16(18)24)21-26-17-3-2-8-33(30,31)20(17)22(27-21)25-14-6-4-12(10-19(28)29)15(23)11-14/h4-7,9,11H,2-3,8,10H2,1H3,(H,28,29)(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Kyushu University Curated by ChEMBL					Assay Description Inhibition of full-length human PDE4B2 assessed as cAMP hydrolysis preincubated for 20 mins followed by cAMP addition measured after 30 mins				Bioorg Med Chem Lett 24: 893-9 (2014) Article DOI: 10.1016/j.bmcl.2013.12.076 BindingDB Entry DOI: 10.7270/Q2GX4FHW
					More data for this Ligand-Target Pair