Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4D' and Ligand = 'BDBM50008744'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM50008744 (CHEMBL3236000) Show SMILES COC1=CC(=O)c2cc(C)cc(c2C1=O)-c1c(OC)cc(OC)c2ccc(=O)oc12 |t:2,(47.77,-52.9,;47.78,-51.36,;46.45,-50.58,;46.45,-49.04,;45.11,-48.26,;45.11,-46.72,;43.78,-49.03,;42.44,-48.27,;41.11,-49.04,;39.78,-48.27,;41.11,-50.58,;42.44,-51.36,;43.77,-50.58,;45.1,-51.35,;45.1,-52.89,;42.44,-54.07,;41.11,-54.83,;39.77,-54.06,;39.77,-52.52,;41.11,-56.37,;42.44,-57.14,;42.45,-58.68,;41.12,-59.46,;43.77,-56.36,;45.1,-57.12,;46.43,-56.36,;46.42,-54.82,;47.76,-54.05,;45.09,-54.05,;43.77,-54.82,)| Show InChI InChI=1S/C23H18O7/c1-11-7-13-15(24)9-18(29-4)22(26)20(13)14(8-11)21-17(28-3)10-16(27-2)12-5-6-19(25)30-23(12)21/h5-10H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human PDE4D2 catalytic domain (86 to 413aa) expressed in Escherichia coli strain BL21 after 15 mins by liquid scintillation counting in...				J Nat Prod 77: 955-62 (2014) Article DOI: 10.1021/np401040d BindingDB Entry DOI: 10.7270/Q2HQ41GQ
					More data for this Ligand-Target Pair