Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM171959'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM171959 (US9085584, 103) Show SMILES Cc1ccc(cc1-c1nnc2c(C)nc3ccc(nc3n12)C1CC1)C1(O)CCOCC1 Show InChI InChI=1S/C24H25N5O2/c1-14-3-6-17(24(30)9-11-31-12-10-24)13-18(14)22-28-27-21-15(2)25-20-8-7-19(16-4-5-16)26-23(20)29(21)22/h3,6-8,13,16,30H,4-5,9-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The inhibition of PDE 2A or 10 enzyme activity was assessed using IMAP-Phosphodiesterase-cAMP fluorescence labeled substrate (Molecular Devices, Orde...				US Patent US9085584 (2015) BindingDB Entry DOI: 10.7270/Q27P8X54
					More data for this Ligand-Target Pair