Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM292713'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM292713 (1-(5-Butoxy-2-chlorophenyl)-8-chloro-3-methyl-1H-p...) Show SMILES CCCCOc1ccc(Cl)c(c1)-n1nc(C)c2c1c1nc(Cl)ccc1[nH]c2=O Show InChI InChI=1S/C20H18Cl2N4O2/c1-3-4-9-28-12-5-6-13(21)15(10-12)26-19-17(11(2)25-26)20(27)23-14-7-8-16(22)24-18(14)19/h5-8,10H,3-4,9H2,1-2H3,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description r-hPDE2A (Accession No. NM_002599, Homo sapiens phosphodiesterase 2A, cGMP-stimulated, transcript variant 1) A mammalian expression cloning vector wi...				US Patent US10543194 (2020) BindingDB Entry DOI: 10.7270/Q2F47RJZ
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM292713 (1-(5-Butoxy-2-chlorophenyl)-8-chloro-3-methyl-1H-p...) Show SMILES CCCCOc1ccc(Cl)c(c1)-n1nc(C)c2c1c1nc(Cl)ccc1[nH]c2=O Show InChI InChI=1S/C20H18Cl2N4O2/c1-3-4-9-28-12-5-6-13(21)15(10-12)26-19-17(11(2)25-26)20(27)23-14-7-8-16(22)24-18(14)19/h5-8,10H,3-4,9H2,1-2H3,(H,23,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.2	25
INTRA-CELLULAR THERAPIES, INC. US Patent					Assay Description Assay: PDE2A is assayed with FL-cAMP as substrate. An enzyme titration is first performed to determine the working concentration of PDE. The concentr...				US Patent US10105349 (2018) BindingDB Entry DOI: 10.7270/Q2QN68T1
					More data for this Ligand-Target Pair