Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50018611'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50018611 (4-Amino-6-(4-imidazol-1-yl-phenyl)-2H-pyridazin-3-...) Show SMILES Nc1cc(n[nH]c1=O)-c1ccc(cc1)-n1ccnc1 Show InChI InChI=1S/C13H11N5O/c14-11-7-12(16-17-13(11)19)9-1-3-10(4-2-9)18-6-5-15-8-18/h1-8H,(H2,14,16)(H,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	8.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against cGMP PDE II enzyme in guinea pig				J Med Chem 30: 1955-62 (1987) BindingDB Entry DOI: 10.7270/Q27S7MS4
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50018611 (4-Amino-6-(4-imidazol-1-yl-phenyl)-2H-pyridazin-3-...) Show SMILES Nc1cc(n[nH]c1=O)-c1ccc(cc1)-n1ccnc1 Show InChI InChI=1S/C13H11N5O/c14-11-7-12(16-17-13(11)19)9-1-3-10(4-2-9)18-6-5-15-8-18/h1-8H,(H2,14,16)(H,17,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10E+5	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibitory concentration against cAMP PDE II enzyme in guinea pig				J Med Chem 30: 1955-62 (1987) BindingDB Entry DOI: 10.7270/Q27S7MS4
					More data for this Ligand-Target Pair