Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50452207'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50452207 (CHEMBL4207765) Show SMILES Cn1ncc2c(NCCc3ccc(cc3)C(F)(F)F)nc(Cl)nc12 Show InChI InChI=1S/C15H13ClF3N5/c1-24-13-11(8-21-24)12(22-14(16)23-13)20-7-6-9-2-4-10(5-3-9)15(17,18)19/h2-5,8H,6-7H2,1H3,(H,20,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Curated by ChEMBL					Assay Description Binding affinity to PDE2 (unknown origin) by SPR analysis				Bioorg Med Chem Lett 27: 5167-5171 (2017) Article DOI: 10.1016/j.bmcl.2017.10.054 BindingDB Entry DOI: 10.7270/Q28C9ZV3
					More data for this Ligand-Target Pair