Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50491649'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50491649 (CHEMBL2387137) Show SMILES CCC(CC)c1nn(CCCO)c2c1N=C(CNC2=O)c1ccc(cc1)-n1ccnc1C |c:15| Show InChI InChI=1S/C24H30N6O2/c1-4-17(5-2)21-22-23(30(28-21)12-6-14-31)24(32)26-15-20(27-22)18-7-9-19(10-8-18)29-13-11-25-16(29)3/h7-11,13,17,31H,4-6,12,14-15H2,1-3H3,(H,26,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	328	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of PDE2 (unknown origin)				Bioorg Med Chem Lett 23: 3438-42 (2013) Article DOI: 10.1016/j.bmcl.2013.03.072 BindingDB Entry DOI: 10.7270/Q2MP5665
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