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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-dependent 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM566470'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
cGMP-dependent 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM566470
PNG
(US11419874, Example 20)
Show SMILES Cc1cnc2c(cnn2c1)C(=O)N[C@@H](c1ccc(OC(F)(F)F)cc1)C(C)(C)O |r|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 5.10n/an/an/an/an/an/a


TBA

Assay Description
Activity at Histamine H3 receptor using functional H3 receptor assay on guinea pig ileum


Citation and Details
More data for this
Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase


(Homo sapiens (Human))
BDBM566470
PNG
(US11419874, Example 20)
Show SMILES Cc1cnc2c(cnn2c1)C(=O)N[C@@H](c1ccc(OC(F)(F)F)cc1)C(C)(C)O |r|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.10n/an/an/an/an/an/a


TBA

Assay Description
Isolated cardiomyocytes were washed twice in PBS at room temperature, transferred to 4% paraformaldehyde (PFA) and gently shaken for 30 min, then was...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2CR5XK9
More data for this
Ligand-Target Pair