Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-dependent protein kinase' and Ligand = 'BDBM50530652'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530652 (CHEMBL4572858) Show SMILES Cc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)on1 Show InChI InChI=1S/C22H21FN6OS/c1-13-12-18(30-29-13)27-22-25-11-8-17(26-22)20-19(14-2-4-16(23)5-3-14)28-21(31-20)15-6-9-24-10-7-15/h2-5,8,11-12,15,24H,6-7,9-10H2,1H3,(H,25,26,27)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase (Plasmodium falciparum)	BDBM50530652 (CHEMBL4572858) Show SMILES Cc1cc(Nc2nccc(n2)-c2sc(nc2-c2ccc(F)cc2)C2CCNCC2)on1 Show InChI InChI=1S/C22H21FN6OS/c1-13-12-18(30-29-13)27-22-25-11-8-17(26-22)20-19(14-2-4-16(23)5-3-14)28-21(31-20)15-6-9-24-10-7-15/h2-5,8,11-12,15,24H,6-7,9-10H2,1H3,(H,25,26,27)	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum full length N-terminal His-tagged PKG expressed in Escherichia coli RosettaTM 2(DE3) pLysS cells using FAM-GRTGRR...				J Med Chem 62: 9217-9235 (2019) Article DOI: 10.1021/acs.jmedchem.9b01099 BindingDB Entry DOI: 10.7270/Q2X63RDP
					More data for this Ligand-Target Pair