Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B' and Ligand = 'BDBM50226902'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50226902 (CHEMBL435758) Show SMILES CN1CCN(CC1)c1ccc2nc(O)nc(C)c2c1 Show InChI InChI=1S/C14H18N4O/c1-10-12-9-11(18-7-5-17(2)6-8-18)3-4-13(12)16-14(19)15-10/h3-4,9H,5-8H2,1-2H3,(H,15,16,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair