Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B' and Ligand = 'BDBM50229793'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50229793 (CHEMBL316367) Show SMILES Oc1nc2cc3cc(OCCCC(=O)N4CCN(CC(=O)N5CCCC5)CC4)ccc3[nH]c2n1 Show InChI InChI=1S/C24H30N6O4/c31-21(30-11-9-28(10-12-30)16-22(32)29-7-1-2-8-29)4-3-13-34-18-5-6-19-17(14-18)15-20-23(25-19)27-24(33)26-20/h5-6,14-15H,1-4,7-13,16H2,(H2,25,26,27,33)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet cAMP Phosphodiesterase PDE 3				J Med Chem 35: 2688-96 (1992) BindingDB Entry DOI: 10.7270/Q2PN97WB
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