Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM150188'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM150188 (US8980904, 13) Show SMILES COc1ccc(COc2nc(ncc2C(=O)NCCN2CCOCC2)N2CC3CC3C2)cc1Cl Show InChI InChI=1S/C24H30ClN5O4/c1-32-21-3-2-16(10-20(21)25)15-34-23-19(22(31)26-4-5-29-6-8-33-9-7-29)12-27-24(28-23)30-13-17-11-18(17)14-30/h2-3,10,12,17-18H,4-9,11,13-15H2,1H3,(H,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.213	n/a	n/a	n/a	n/a	7.5	30
Xuanzhu Pharma Co., Ltd. US Patent					Assay Description A sample to be tested is precisely weighed, dissolved by adding DMSO, mixed sufficiently to form 10 mM solution. The above mother solution is diluted...				US Patent US8980904 (2015) BindingDB Entry DOI: 10.7270/Q24M9389
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