Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM157146'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM157146 (US9023849, 16) Show SMILES Cc1ncc2c(nn(Cc3ccccc3F)c2n1)-c1nnc2c(NC(=O)C2(C)C)n1 Show InChI InChI=1S/C20H17FN8O/c1-10-22-8-12-14(16-24-17-15(26-27-16)20(2,3)19(30)25-17)28-29(18(12)23-10)9-11-6-4-5-7-13(11)21/h4-8H,9H2,1-3H3,(H,24,25,27,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...				US Patent US9023849 (2015) BindingDB Entry DOI: 10.7270/Q2TD9W3Q
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