Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM157147'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM157147 (US9023849, 17) Show SMILES Cc1ncc2c(nn(Cc3cccc(F)c3F)c2n1)-c1ncc2c(NC(=O)C2(C)C)n1 Show InChI InChI=1S/C21H17F2N7O/c1-10-24-7-12-16(18-25-8-13-17(27-18)28-20(31)21(13,2)3)29-30(19(12)26-10)9-11-5-4-6-14(22)15(11)23/h4-8H,9H2,1-3H3,(H,25,27,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...				US Patent US9023849 (2015) BindingDB Entry DOI: 10.7270/Q2TD9W3Q
					More data for this Ligand-Target Pair