Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM157156'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM157156 (US9023849, 27) Show SMILES Cc1nc(nc2NC(=O)C(C)(C)c12)-n1nc(Cc2ccccc2F)c2cc(F)ccc12 Show InChI InChI=1S/C23H19F2N5O/c1-12-19-20(27-21(31)23(19,2)3)28-22(26-12)30-18-9-8-14(24)11-15(18)17(29-30)10-13-6-4-5-7-16(13)25/h4-9,11H,10H2,1-3H3,(H,26,27,28,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	7.5	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description To determine their in vitro action on human PDE 5, the test substances are dissolved in 100% DMSO and serially diluted. Typically, dilution series (1...				US Patent US9023849 (2015) BindingDB Entry DOI: 10.7270/Q2TD9W3Q
					More data for this Ligand-Target Pair