Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM236642'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM236642 (US9388139, 10) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)C(O)=O)c1ccc(OC)c(OC)c1 |c:11| Show InChI InChI=1S/C25H24N2O5/c1-30-20-11-6-16(7-12-20)22-15-21(18-8-13-23(31-2)24(14-18)32-3)26-27(22)19-9-4-17(5-10-19)25(28)29/h4-14,22H,15H2,1-3H3,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant full length GST-tagged PDE5A1 (unknown origin) expressed in baculovirus infected Sf9 insect cells using TAMRA-cGMP as subst...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01120 BindingDB Entry DOI: 10.7270/Q2765K34
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM236642 (US9388139, 10) Show SMILES COc1ccc(cc1)C1CC(=NN1c1ccc(cc1)C(O)=O)c1ccc(OC)c(OC)c1 |c:11| Show InChI InChI=1S/C25H24N2O5/c1-30-20-11-6-16(7-12-20)22-15-21(18-8-13-23(31-2)24(14-18)32-3)26-27(22)19-9-4-17(5-10-19)25(28)29/h4-14,22H,15H2,1-3H3,(H,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
German University; Southern Research Institute US Patent					Assay Description PDE activity was measured using the IMAP fluorescence polarization assay (Molecular Devices) in which binding of hydrolyzed cyclic nucleotide substra...				US Patent US9388139 (2016) BindingDB Entry DOI: 10.7270/Q2GF0SFS
					More data for this Ligand-Target Pair