Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM480503'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM480503 (US10626113, Compound N | US10899756, Compound V) Show SMILES COc1ccc(cc1Cl)C(C)Nc1c2CN(CCc2nc2ccc(cc12)C#N)C(C)=O Show InChI InChI=1S/C24H23ClN4O2/c1-14(17-5-7-23(31-3)20(25)11-17)27-24-18-10-16(12-26)4-6-21(18)28-22-8-9-29(15(2)30)13-19(22)24/h4-7,10-11,14H,8-9,13H2,1-3H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	26.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2KH0SFD
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM480503 (US10626113, Compound N | US10899756, Compound V) Show SMILES COc1ccc(cc1Cl)C(C)Nc1c2CN(CCc2nc2ccc(cc12)C#N)C(C)=O Show InChI InChI=1S/C24H23ClN4O2/c1-14(17-5-7-23(31-3)20(25)11-17)27-24-18-10-16(12-26)4-6-21(18)28-22-8-9-29(15(2)30)13-19(22)24/h4-7,10-11,14H,8-9,13H2,1-3H3,(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.9	n/a	n/a	n/a	n/a	n/a	n/a
The Trustees of Columbia University in the City of New York US Patent					Assay Description A series of dilutions of the test compounds were prepared with 10% DMSO in assay buffer and 5 μl of the dilution was added to a 50 μl react...				US Patent US10899756 (2021) BindingDB Entry DOI: 10.7270/Q2RN3C0P
					More data for this Ligand-Target Pair