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Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50017097'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-specific 3',5'-cyclic phosphodiesterase


(Bos taurus)		BDBM50017097
PNG
(1-Benzoyl-4-(3,4-dimethoxy-phenyl)-pyrrolidin-2-on...)
Show SMILES COc1ccc(cc1OC)C1CN(C(=O)c2ccccc2)C(=O)C1
Show InChI InChI=1S/C19H19NO4/c1-23-16-9-8-14(10-17(16)24-2)15-11-18(21)20(12-15)19(22)13-6-4-3-5-7-13/h3-10,15H,11-12H2,1-2H3
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PubMed
n/an/a>1.00E+6n/an/an/an/an/an/a



Centre de Neurochimie du CNRS

Curated by ChEMBL


Assay Description
Inhibition of cGMP-PDE phosphodiesterase from bovine aorta using 1 uM cGMP (insignificant)

J Med Chem 32: 1450-7 (1989)


BindingDB Entry DOI: 10.7270/Q2DN441H
More data for this
Ligand-Target Pair