Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50059066'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50059066 ((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-2,5-dimethyl-3-(...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(C)n(Cc3ccccc3)c2C1=O |t:2| Show InChI InChI=1S/C19H21N5O/c1-12-20-17-16(23(12)11-13-7-4-3-5-8-13)18(25)22(2)19-21-14-9-6-10-15(14)24(17)19/h3-5,7-8,14-15H,6,9-11H2,1-2H3/t14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Evaluated for inhibitory activity against Phosphodiesterase 5 (PDE5) purified from bovine lung				J Med Chem 40: 2196-210 (1997) Article DOI: 10.1021/jm9608467 BindingDB Entry DOI: 10.7270/Q2G44PFZ
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50059066 ((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-2,5-dimethyl-3-(...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(C)n(Cc3ccccc3)c2C1=O |t:2| Show InChI InChI=1S/C19H21N5O/c1-12-20-17-16(23(12)11-13-7-4-3-5-8-13)18(25)22(2)19-21-14-9-6-10-15(14)24(17)19/h3-5,7-8,14-15H,6,9-11H2,1-2H3/t14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
Banasthali University Curated by ChEMBL					Assay Description Inhibition of PDE5 (unknown origin)				Bioorg Med Chem Lett 24: 3137-41 (2014) Article DOI: 10.1016/j.bmcl.2014.05.004 BindingDB Entry DOI: 10.7270/Q2JH3NRM
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Bos taurus)	BDBM50059066 ((6aR,9aS)-5,6a,7,8,9,9a-Hexahydro-2,5-dimethyl-3-(...) Show SMILES CN1C2=N[C@@H]3CCC[C@@H]3N2c2nc(C)n(Cc3ccccc3)c2C1=O |t:2| Show InChI InChI=1S/C19H21N5O/c1-12-20-17-16(23(12)11-13-7-4-3-5-8-13)18(25)22(2)19-21-14-9-6-10-15(14)24(17)19/h3-5,7-8,14-15H,6,9-11H2,1-2H3/t14-,15+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 5 from bovine lung				J Med Chem 40: 4372-7 (1998) Article DOI: 10.1021/jm970495b BindingDB Entry DOI: 10.7270/Q2833R45
					More data for this Ligand-Target Pair