Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50125117'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50125117 ((1-Benzo[1,3]dioxol-5-yl-3,4-dihydro-1H-benzo[4,5]...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1ccc(o1)C(=O)N1CCc2c(sc3ccccc23)C1c1ccc2OCOc2c1 Show InChI InChI=1S/C29H20N2O6S/c32-29(24-11-10-22(37-24)17-4-3-5-19(14-17)31(33)34)30-13-12-21-20-6-1-2-7-26(20)38-28(21)27(30)18-8-9-23-25(15-18)36-16-35-23/h1-11,14-15,27H,12-13,16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Inhibitory activity against PDE5 from human corpus cavernosum				Bioorg Med Chem Lett 13: 761-5 (2003) BindingDB Entry DOI: 10.7270/Q29886CM
					More data for this Ligand-Target Pair