Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50125133'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50125133 (1-Benzo[1,3]dioxol-5-yl-2-(5-p-tolyl-pyrimidin-2-y...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1)N1CCc2c([nH]c3ccccc23)C1c1ccc2OCOc2c1 Show InChI InChI=1S/C29H24N4O2/c1-18-6-8-19(9-7-18)21-15-30-29(31-16-21)33-13-12-23-22-4-2-3-5-24(22)32-27(23)28(33)20-10-11-25-26(14-20)35-17-34-25/h2-11,14-16,28,32H,12-13,17H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	543	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development L.L.C. Curated by ChEMBL					Assay Description Inhibitory activity against PDE5 from human corpus cavernosum				Bioorg Med Chem Lett 13: 761-5 (2003) BindingDB Entry DOI: 10.7270/Q29886CM
					More data for this Ligand-Target Pair