Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM50163582'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Rattus norvegicus)	BDBM50163582 (2-[2,2'']Bipyridinyl-5-yl-3-(2,3-dihydro-benzofura...) Show SMILES Oc1c2CN(C(c2nc2ccccc12)c1ccc2OCCc2c1)c1ccc(nc1)-c1ccccn1 Show InChI InChI=1S/C29H22N4O2/c34-29-21-5-1-2-6-23(21)32-27-22(29)17-33(28(27)19-8-11-26-18(15-19)12-14-35-26)20-9-10-25(31-16-20)24-7-3-4-13-30-24/h1-11,13,15-16,28H,12,14,17H2,(H,32,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of phosphodiesterase 5 in rat fetal lung fibroblast (RFL-6) cells				J Med Chem 48: 2126-33 (2005) Article DOI: 10.1021/jm0401098 BindingDB Entry DOI: 10.7270/Q2WH2QR5
					More data for this Ligand-Target Pair